Aortic Systolic and Pulse Pressure and Type 1 Diabetes
This is the first study to measure 24 h-CASP and 24 h-CPP in patients with type 1 diabetes. The 24 h-CASP and 24 h-CPP was increased in patients with type 1 diabetes compared to controls and increased with albuminuria, CVD, retinopathy and autonomic dysfunction independently of covariates. Furthermore, 24 h-CASP appeared to be stronger associated with complications as compared to 24 h-SBP. As measurement of 24 h ambulatory central BP is now feasible, further studies are required to determine its prognostic significance in patients with diabetes.
Conclusions
This is the first study to measure 24 h-CASP and 24 h-CPP in patients with type 1 diabetes. The 24 h-CASP and 24 h-CPP was increased in patients with type 1 diabetes compared to controls and increased with albuminuria, CVD, retinopathy and autonomic dysfunction independently of covariates. Furthermore, 24 h-CASP appeared to be stronger associated with complications as compared to 24 h-SBP. As measurement of 24 h ambulatory central BP is now feasible, further studies are required to determine its prognostic significance in patients with diabetes.