There are many different treatment methods available for nail fungus. The advantage of western medicines is that they have clear healing efficacy and powerful lethal effect to infectious agent because they are usually chemical substances. Yet at the same time, as western medicines have certain side effect more or less, some present toxic side effect obviously and even can cause serious drug-induced diseases and drug resistance. Below is the comparison of chemical drugs and natural drugs for nail fungus.
Terbinafine is an allylamine antifungal agent that is active against dermatophytes, which are responsible for the majority of nail fungus cases. Consequently, liver enzyme levels and a complete blood count should be obtained before terbinafine is initiated and repeated every four to six weeks during treatment. Studies have shown that the regimen for toenails results in a mycologic cure rate of seventy one to eighty two percent and a clinical cure rate of sixty to seventy percent. This agent is notably less effective against nondermatophytes, including Candida species and molds.
Because of its hepatic metabolism, terbinafine has several important drug interactions. Terbinafine should be discontinued if the aspartate aminotransferase or alanine aminotransferase level becomes elevated to two or more times normal. Side effects are uncommon and resolve with discontinuation of the drug. However, adverse effects, including headache, rash and gastrointestinal upset, are reported more often with terbinafine than with placebo. Rare but serious complications have been reported in patients treated with terbinafine.
Itraconazole is a newer triazole medication with a broad antifungal spectrum. Itraconazole is also contraindicated for concomitant use with reductase inhibitors because of the increased risk of rhabdomyolysis. The FDA has labeled pulse therapy only for the treatment of fingernail infections. Pulse treatment consists of two hundred mg taken twice daily for one week per month, with the treatment repeated for two to three months. This dosage, given in three to four pulses, has also been shown to be effective in the treatment of toenail infections.
Published studies have demonstrated similar success rates for continuous and pulse therapies, with mycologic cure rates ranging from forty five to seventy percent and clinical cure rates ranging from thirty five to eighty percent. Although hepatic toxicity is rare, headache, rash and gastrointestinal upset occur in about seven percent of treated patients. Because itraconazole is metabolized by the hepatic cytochrome P450 system, significant drug interactions can occur. Notably, concurrent use with quinidines and pimozide is contraindicated because of the risk of ventricular arrhythmias.
In addition, itraconazole should not be taken with some benzodiazepines, such as midazolam and triazolam, because of exaggerated sedation and potential airway compromise. Increased gastric pH decreases the absorption of itraconazole. Therefore, the effectiveness of this antifungal agent can be decreased by histamine H2 blockers, and by proton pump inhibitors. It is thus clear that western medicines cause serious harm to the body at the time of dealing with diseases. The toxicity issue of western medicines is an increasing concern.
As a result, it is very difficult to create an effective antifungal drug that does not also damage the human system. Try natural plant medicine for nail fungus. Plant medicine contains very potent certified organic medicinal plant extracts and antifungal essential oils. These extracts exhibit a wide spectrum of antifungal activity, and they have demonstrated their ability to kill the fungi causing nail fungus infections. This is a painless yet strong treatment, delivering remarkable results in the elimination of nail fungus.
Natural plant medicine returns the nail to its original state prior to the onset of the infection. As the treatment can effectively eliminate nail fungus, prescription medications for nail fungus may soon become a thing of the past. The side effects of toxins introduced into your system should not be taken lightly. If you are in need of a truly effective, pure, and natural nail fungus treatment, plant medicine represents a very effective, trusted, and safe method to reverse the condition. To learn more, please go to http://www.naturespharma.org.
Terbinafine is an allylamine antifungal agent that is active against dermatophytes, which are responsible for the majority of nail fungus cases. Consequently, liver enzyme levels and a complete blood count should be obtained before terbinafine is initiated and repeated every four to six weeks during treatment. Studies have shown that the regimen for toenails results in a mycologic cure rate of seventy one to eighty two percent and a clinical cure rate of sixty to seventy percent. This agent is notably less effective against nondermatophytes, including Candida species and molds.
Because of its hepatic metabolism, terbinafine has several important drug interactions. Terbinafine should be discontinued if the aspartate aminotransferase or alanine aminotransferase level becomes elevated to two or more times normal. Side effects are uncommon and resolve with discontinuation of the drug. However, adverse effects, including headache, rash and gastrointestinal upset, are reported more often with terbinafine than with placebo. Rare but serious complications have been reported in patients treated with terbinafine.
Itraconazole is a newer triazole medication with a broad antifungal spectrum. Itraconazole is also contraindicated for concomitant use with reductase inhibitors because of the increased risk of rhabdomyolysis. The FDA has labeled pulse therapy only for the treatment of fingernail infections. Pulse treatment consists of two hundred mg taken twice daily for one week per month, with the treatment repeated for two to three months. This dosage, given in three to four pulses, has also been shown to be effective in the treatment of toenail infections.
Published studies have demonstrated similar success rates for continuous and pulse therapies, with mycologic cure rates ranging from forty five to seventy percent and clinical cure rates ranging from thirty five to eighty percent. Although hepatic toxicity is rare, headache, rash and gastrointestinal upset occur in about seven percent of treated patients. Because itraconazole is metabolized by the hepatic cytochrome P450 system, significant drug interactions can occur. Notably, concurrent use with quinidines and pimozide is contraindicated because of the risk of ventricular arrhythmias.
In addition, itraconazole should not be taken with some benzodiazepines, such as midazolam and triazolam, because of exaggerated sedation and potential airway compromise. Increased gastric pH decreases the absorption of itraconazole. Therefore, the effectiveness of this antifungal agent can be decreased by histamine H2 blockers, and by proton pump inhibitors. It is thus clear that western medicines cause serious harm to the body at the time of dealing with diseases. The toxicity issue of western medicines is an increasing concern.
As a result, it is very difficult to create an effective antifungal drug that does not also damage the human system. Try natural plant medicine for nail fungus. Plant medicine contains very potent certified organic medicinal plant extracts and antifungal essential oils. These extracts exhibit a wide spectrum of antifungal activity, and they have demonstrated their ability to kill the fungi causing nail fungus infections. This is a painless yet strong treatment, delivering remarkable results in the elimination of nail fungus.
Natural plant medicine returns the nail to its original state prior to the onset of the infection. As the treatment can effectively eliminate nail fungus, prescription medications for nail fungus may soon become a thing of the past. The side effects of toxins introduced into your system should not be taken lightly. If you are in need of a truly effective, pure, and natural nail fungus treatment, plant medicine represents a very effective, trusted, and safe method to reverse the condition. To learn more, please go to http://www.naturespharma.org.