Differentiating Takotsubo Cardiomyopathy From Acute MI
Differentiating Takotsubo Cardiomyopathy From Acute MI
Here, we, for the first time, describe a signature of circulating miRNAs for sensitive and specific identification of TTC in the acute phase. This signature may hold great promise to become an important diagnostic tool for the immediate diagnosis of TTC. The significant up-regulation of stress- and depression-related miRNAs suggests a role of central and/or peripheral nervous system in TTC. Furthermore, our findings suggest that ET-1 may play a role in the pathomechanism of TTC.
Conclusion
Here, we, for the first time, describe a signature of circulating miRNAs for sensitive and specific identification of TTC in the acute phase. This signature may hold great promise to become an important diagnostic tool for the immediate diagnosis of TTC. The significant up-regulation of stress- and depression-related miRNAs suggests a role of central and/or peripheral nervous system in TTC. Furthermore, our findings suggest that ET-1 may play a role in the pathomechanism of TTC.