Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

• Nonsteroidal anti-inflammatory drugs include over-the-counter medications like Aleve and Motrin. The body produces a chemical called prostaglandins that help the platelets form blood clots and protect the lining of the stomach from damage caused by acid. Prostaglandins also produce inflammation, pain and swelling in the joints. NSAIDs were developed to reduce the production of prostaglandins.
  
  

Corticosteroid

• Corticosteroid medications, such as the generic prednisone and methylprednisolone (Medrol), reduce inflammation and pain. Their anti-inflammatory properties are particularly potent with immune system conditions that affect the joints such as rheumatoid arthritis.
  
  

Disease-Modifying Antirheumatic Drugs (DMARDs)

• DMARDs are prescribed to treat different kinds of joint and arthritic disorders. They limit joint destruction and ease the symptoms caused by rheumatoid arthritis and other painful conditions. Common DMARDs include hydroxychloroquine (Plaquenil), auranofin (Ridaura), sulfasalazine (Azulfidine), minocycline (Dynacin, Minocin) and methotrexate (Rheumatrex).
  
  

TNF-Alpha Inhibitors

• TNF-alpha is a cell protein that acts as an anti-inflammatory against rheumatoid arthritis. TNF inhibitors help block pain, reduce morning stiffness and joint pain and inflammation. It takes about two weeks for TNF-alpha inhibitors to begin working. TNF-alpha inhibitors on the market include etanercept (Enbrel), infliximab (Remicade) and adalimumab (Humira).
  
  

Supplements

• Supplements such as glucosamine, chondroitin, and turmeric may help improve flexibility and reduce symptoms of osteoarthritis and other painful joint diseases. These are herbal supplements that offer an alternative to prescription medications.