Improvements in Recanalization With Modern Stroke Therapy
This review of prospective acute ischemic stroke trial results since 1999 indicates a substantial improvement in revascularization. However, in the setting of a significant increase in time to treatment onset, no appreciable change in good functional outcome was identified. While the results presented here indicate exciting progress in treatment of acute stroke over the last two decades, it is evident that there is much work to be done in translating improved recanalization to improved patient functional outcomes.
Conclusions
This review of prospective acute ischemic stroke trial results since 1999 indicates a substantial improvement in revascularization. However, in the setting of a significant increase in time to treatment onset, no appreciable change in good functional outcome was identified. While the results presented here indicate exciting progress in treatment of acute stroke over the last two decades, it is evident that there is much work to be done in translating improved recanalization to improved patient functional outcomes.