Gastrointestinal Problems

• The gastrointestinal problems caused by Solu-Medrol may include nausea, vomiting and indigestion.
  
  

Weight Gain

• An increased appetite while taking Solu-Medrol is a common side effect that leads to weight gain. The amount of weight gain differs from person to person.
  
  

Sleep Disturbances

• Sleep disturbances may occur like insomnia, tossing and turning, and the inability to stay asleep.
  
  

Fluid Retention

• Fluid retention or edema causes the hands, feet, legs, arms and face to swell from excess fluid. This side effect can lead to congestive heart failure in patients with a history of heart problems.
  
  

Mucle Weakness

• Muscle weakness and loss of muscle mass are two side effects from Solu-Medrol.
  
  

Neurological Problems

• Neurological problems may include headaches, convulsions and vertigo. Vertigo is characterized as feeling dizzy, unable to regain balance and can cause vomiting. Contact your doctor immediately if you experience a convulsions.