Fetal Injury

• A rare complication of amniocentesis involves injuring the fetus with the needle used to collect amniotic fluid. To reduce this risk, make sure that your physician has performed successful amniocenteses in the past.
  
  

Miscarriage

• There is also a slight risk of miscarriage with women who have had amniocentesis; however, a direct correlation between the procedure and miscarriages has not yet been demonstrated. Inform your physician if there is a history of miscarriage or premature birth in your family. Your doctor may recommend delaying amniocentesis or performing a different type of fetal diagnostic exam.
  
  

Repeat Procedures

• A slight chance exists that the physician performing the amniocentesis will not gather enough fluid to make an accurate diagnosis. Having an experienced doctor, as well as a capable sonographer to assist him or her, reduces your odds of needing a second amniocentesis.